Expert Talks
We host a series of online journal clubs, highlighting the use and the applications of our products. Scientists present their projects and new data, and you can learn about the latest developments in the field. We always schedule time for Q&A at the end of the presentation so that you can ask your questions and discuss the findings.
Journal Clubs and Webinars
Q&A available
Thursday, 19 Oct 2023
Journal Club: Monitoring Refractive Development in Mice to Investigate Mechanisms of Myopia
Reece Mazade, Ph.D. - Emory University School of Medicine, Pardue Lab
This Journal Club will demonstrate the usefulness and feasibility of refractive error measurements in mice, and it will discuss how measurements with Striatech’s automated Photorefractor can elucidate mechanisms of refractive development.
- Related Products:
- PhotoRefractor
Sunday, 17 Sep 2023
Symposium: Opportunities, Hopes, and Challenges in Translating Visual Restoration from Mouse to Human
Professor Eberhart Zrenner - Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen
Constance Cepko, PhD - Harvard Medical School
Miikka Terho, MBA - Pioneer Retina Implant Patient, Finland
Striatech celebrates its 5th anniversary with a top-class Symposium on the topic of translating visual restoration from mouse to human. Presentations will be given by Professor Eberhart Zrenner (University of Tübingen), Professor Constance Cepko (Harvard Medical School) and Miikka Terho (Pioneer Retina Implant Patient, Finland). In addition, the speakers will highlight important aspects and directions in this area of research in a moderated panel discussion.
- Related Products:
- OptoDrum
Q&A available
Wednesday, 21 Jun 2023
Journal Club: Postsynaptic Neuronal Activity Promotes Retinal Axon Regeneration
Supraja Varadarajan, Ph.D. - Stanford University, School of Medicine, Huberman Lab
This Journal Club provides insights into mechanisms that promote retinal ganglion cell (RGC) axon regeneration in vertebrates after optic nerve injury.
- Related Products:
- OptoDrum
Q&A available
Wednesday, 05 Apr 2023
Journal Club: Inherited Retinal Dystrophy: Chronic Proinflammatory Signaling Accelerates the Rate of Degeneration
T.J. Hollingsworth, PhD - University of Tennessee Health Science Center
T.J. Hollingsworth presents his work where he characterized a new polygenic mouse model of inherited retinal dystrophies, the BXD32 mouse strain. He presents evidence that a proinflammatory environment in the retina supports and accelerates the degeneration of the retina and the loss of visual function.
- Related Products:
- OptoDrum
Q&A available
Wednesday, 25 Jan 2023
Journal Club: Developing Retinal Gene Therapy for Zellweger Spectrum Disorder (ZSD)
Catherine Argyriou, PhD - McGill University, Dept of Human Genetics
Peroxisomal disorders and the PEX1-G844D mouse model for mild Zellweger Spectrum Disorder (ZSD), leads to retinal degeneration and vision loss. Catherine Argyriou will describe how her team used AAV8-mediated gene delivery to robustly and durably improve functional vision, retinal response, retinal structure, and biochemical metabolites in ZSD-mice.
- Related Products:
- OptoDrum
Q&A available
Wednesday, 09 Nov 2022
Journal Club: In Vivo Modeling of Immune-mediated Optic Neuropathies
Oliver W. Gramlich, Ph.D. - The University of Iowa
This presentation will outline the pathobiology and visual phenotype of immune mediated optic neuropathies that include Multiple Sclerosis (MS), Neuromylitis optica spectrum disorders (NMOSD), and Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
- Related Products:
- OptoDrum
Q&A available
Wednesday, 20 Jul 2022
Journal Club: Endothelial Caspase-9 Mediates Inflammatory and Vision Function Changes in Retinal Vascular Injury
Crystal Colón Ortiz, Ph.D. - Columbia University Medical Center
In retinal vein occlusion (RVO), non-apoptotic expression of endothelial caspase-9 (EC Casp9) induces pathology including retinal edema, capillary ischemia, and neurodegeneration. Crystal Colón Ortiz presents mechanistic insights into EC Casp9 action, and the behavioral consequences such as contrast sensitivity decline.
- Related Products:
- OptoDrum
- Applications:
Q&A available
Tuesday, 22 Mar 2022
Journal Club: Anti-FcRn Treatment in Antibody-Associated Experimental Autoimmune Encephalomyelitis
Jana Remlinger, MSc - Department of Neurology, Inselspital, Bern University Hospital and Department for BioMedical Research (DBMR)
Jana Remlinger et al. showed preserved visual function and ameliorated course of disease after anti-FcRn treatment in an experimental model using a monoclonal MOG-IgG to mimic MOGAD.
- Related Products:
- OptoDrum
Wednesday, 17 Nov 2021
Webinar: AcuiSee – Rodent Visual Acuity Using Behavioral Conditioning
Dr. Jeffrey A Jamison - Experimentica Ltd.
In this Webinar, Dr. Jeff Jamison will talk about “AcuiSee”, with which one can measure rodent vision based on an operant conditioning paradigm. Jeff is the developer of AcuiSee, and he now works as Director of In-Vivo Pharmacology at Experimentica.
- Related Products:
- AcuiSee
Q&A available
Thursday, 07 Oct 2021
Journal Club: IR Photorefraction and IR Photokeratometry – Measuring Refractive State and Corneal Curvature in Animals and Humans
Prof. Frank Schaeffel - University of Tübingen, Germany
It is difficult to measure small eyes of animal models. In this Journal Club, Prof. Frank Schaeffel presents his inventions for IR photorefraction and IR photokeratometry that facilitate such measurements. He focuses on the history, application, advantages, optics, software algorithms and calibration.
- Applications:
- Myopia
Q&A available
Thursday, 22 Jul 2021
Journal Club: Echolocation with Light – A New Form of Active Sensing in Fish?
Prof. Nico K. Michiels - University of Tübingen, Germany
Some fish use active photolocation: Their eyes emit light to detect predators or pray in this spotlight. In this Journal Club, Prof. Nico Michiels from the University of Tübingen will talk about his fascinating journey in which he has discovered this phenomenon.
- Related Products:
- OptoDrum
- Applications:
- Vision Science
Q&A available
Thursday, 27 May 2021
Journal Club: Assessing Neuroinflammation-related Neural Damage by Monitoring the Retinotectal System
PD Dr. Janos Groh - Department of Neurology, Section of Developmental Neurobiology, University Hospital Würzburg
Neuroinflammation amplifies neural damage caused by genetic disorders or aging. Groh et al show that neuroinflammation has deleterious consequences for the optic nerve, and disease progression can be monitored with the OptoDrum.
- Related Products:
- OptoDrum
Q&A available
Thursday, 25 Mar 2021
Journal Club: Restoring vision – Optogenetic gene therapy targeted at human ON-bipolar cells
Dr. Elmar Hulliger - Institute of Physiology, University of Bern
Optogenetic gene therapy holds great promise for healing blindness. Hulliger et al have developed a new promoter that effectively targets human ON bipolar cells. This is an important step towards clinical applications of optogenetic gene therapy for restoring vision.
- Related Products:
- OptoDrum
Q&A available
Thursday, 28 Jan 2021
Journal Club: The role of Nogo-A in visual deficits induced by retinal injury.
Julius Baya Mdzomba, PhD - Université Laval
Nogo-A, an inhibitor of neural growth, prevents regeneration after injury. Blocking of Nogo-A aides recovery, also in the visual system after retinal damage. Baya Mdzomba show with our OptoDrum that visual behavior benefits from Nogo-A neutralization after retinal damage typically found in diabetic retinopathy or glaucoma.
- Related Products:
- OptoDrum
Thursday, 08 Oct 2020
Webinar: Visual Acuity as a Relevant Phenotype in Mouse Models of Rare Disease
Zoë Bichler, PhD - The Jackson Laboratory
Maximiliano Presa, PhD - The Jackson Laboratory
The Jackson Laboratory will introduce their Neurobehavior Phenotyping Core, in which they also do visual acuity measurements. They will present two examples where the OptoDrum has been used to characterizte vision in animal models for rare disease: The Charcot-Marie-Tooth-disease, and Multiple-Sulfatase-Deficiency.
- Related Products:
- OptoDrum